Mar 9, 2020
Oliver Rando is a professor
and head of the Rando Lab at the University of
Massachusetts Medical School. He joins the show to discuss his
research on epigenetic inheritance.
You’ll learn the following:
When data that doesn’t belong to the
DNA sequence itself affects the phenotype of an organism in some
way, and when that phenotypic change is passed on from a parent to
a child, epigenetic inheritance is said to occur. It was only two
or three decades ago that there was near consensus in the
scientific community that epigenetic information could not be
passed between generations.
However, a growing number of research studies are now showing that that’s simply not the case. One such study is taking place in Oliver Rando’s lab, where he and his team are using mouse models to demonstrate that the environmental conditions of a father can impact the phenotype of the father’s offspring.
In addition to discussing the details of his research, Rando touches on the nature of some other interesting types of research going on in the area of epigenetic inheritance. He also talks about the limitations and gaps in this type of research, and what he aims to accomplish in the coming years.
Tune in for the full conversation and learn more at https://www.umassmed.edu/randolab/.