May 19, 2021
"The evolution of the nucleus may have initially occurred . . .
because of this coevolutionary dynamic with giant viruses," says
Professor Frank Aylward. He shares several mysterious tidbits of
giant virus evolution and how these particles may have caused
evolutionary pressures that produced everything from the silica
shell of diatoms to cellular metabolism.
Listen and learn
- What determines giant viruses, an interesting group of DNA viruses that infect eukaryotes,
- How scientists think microbial evolution led to their large size,
- What genomics and bioinformatics tells scientists about giant viral genomes and why they're still surrounded by mystery, and
- Why giant virus genome evolution indicates some exciting dynamics of viral indigenization.
Frank Aylward is an assistant professor of biological sciences,
at Virginia Tech. He specializes in
microbial diversity and is fascinated by the abundance of
microbes "that play critical roles in human health, the evolution
of life on Earth, biogeochemical cycling, and the biosphere."
Lately, he's focuses on giant viruses. These viruses are distinct
for their size and their propensity to only infect eukaryotes. This
means, for example, that while giant viruses and bacteriophage have
different domain hosts, they're just as abundant, present in waters
alongside
marine bacteria, in soil, and even in freshwater.
He shares numerous fascinating aspects of what these viruses
tell us about our world. For example, they may have developed their
size from an evolutionary effort of tricking amoeba into eating
them. They practice biological mimicry, mimicking the look of the
microbes that amoeba like to eat, so the amoeba will phagocytose
it: the Mimi virus actually stands for mimicking microbe. Professor
Aylward shares more about the natural history of these viruses,
down to their connection with cellular nuclei and metabolism.
Listen in for more about the magic in microbial diversity.
Episode also available on Apple
Podcasts: apple.co/30PvU9C